Fig. 1

Basal oxidative status of human mammary epithelial cells. a: Basal fluorescence of dihydroethidine (DHE) for cytosolic ROS production. b: Basal cell content for total glutathione. c: Basal cell content for free protein thiols. d: Catalytic activity for glutathione reductase (GR). e: Catalytic activity for glutathione peroxidase 1 (GPx1). f: Catalytic activity for glutathione S-transferase (GST). g: Catalytic activity for heme oxygenase (HO-1). h: Basal production of 8-iso-PGF2α in culture medium. i: Catalytic activity for cyclooxygenase 2 (COX-2). Values are expressed as mean ± standard deviation (n = 6). Between-groups comparison was performed by one-way ANOVA followed by the Kruskal-Wallis multiple comparison test. The significance level was set at 0.05. Different letters (a ≠ b ≠ c, p < 0.05) indicate statistical significance between groups