Table 4 The clinicopathological analyses of BC-1514 (C15), BC-1514 (W12), CD1d, and PJA2. Median (average, IQR), * p < 0.05
Parameter | Cases (percentage) | BC-1514 (C15) | P value | BC-1514 (W12) | P value | CD1d | P value | PJA2 | P value | |
|---|---|---|---|---|---|---|---|---|---|---|
Age | ||||||||||
< 55 | 115 (39.1) | 180 (160.7, 90–200) | 0.903 | 200 (212.4, 200–300) | 0.245 | 90 (98.2, 60–180) | 0.182 | 180 (157.3, 90–200) | 0.956 | |
≥ 55 | 179 (60.9) | 180 (162.5, 100–200) | 200 (225.7, 200–300) | 95 (113.8, 60–180) | 180 (155.5, 90–200) | |||||
pT | ||||||||||
I-II | 281 (95.6) | 180 (161.1, 90–200) | 0.368 | 200 (218.2, 200–300) | 0.015* | 90 (108.1, 60–180) | 0.413 | 180 (155.9, 90–200) | 0.445 | |
III-IV | 13 (4.4) | 200 (177.5, 100–300) | 300 (266.7, 200–300) | 90 (100.0, 10–180) | 200 (163.8, 100–200) | |||||
pN | ||||||||||
pN0 | 192 (65.3) | 180 (163.9, 90–200) | 0.709 | 200 (221.6, 200–300) | 0.979 | 90 (109.8, 70–190) | 0.466 | 180 (157.3, 90–200) | 0.99 | |
pN1 or above | 102 (34.7) | 180 (157.9, 95–200) | 200 (218.9, 200–300) | 90 (103.9, 40–180) | 180 (154.1, 90–200) | |||||
Distant metastasis | ||||||||||
M0 | 289 (98.3) | 180 (160.5, 90–200) | 0.121 | 200 (219.4, 200–300) | 0.09 | 90 (108.1, 60–180) | 0.696 | 180 (155.8, 90–200) | 0.222 | |
M1 | 5 (1.7) | 250 (215.0, 105–300) | 300 (266.7, 200–300) | 90 (92.0, 45–135) | 200 (180.0, 150–200) | |||||
pStage | ||||||||||
I-II | 247 (84.0) | 180 (161.5, 90–200) | 0.525 | 200 (220.1, 200–300) | 0.448 | 90 (107.2, 60–180) | 0.868 | 180 (155.3, 90–200) | 0.416 | |
III-IV | 47 (16.0) | 200 (162.9, 100–200) | 200 (222.5, 200–300) | 90 (110.7, 50–190) | 200 (161.0, 100–200) | |||||
Histological grade | ||||||||||
1 or 2 | 230 (78.2) | 180 (158.7, 90–200) | 0.176 | 200 (214.1, 200–300) | 0.009* | 90 (107.4, 60–180) | 0.832 | 180 (158.2, 95–200) | 0.498 | |
3 | 64 (21.8) | 200 (172.6, 100–200) | 200 (242.4, 200–300) | 95 (109.2, 60–180) | 180 (149.1, 90–200) | |||||
Lymphatic vessel invasion | ||||||||||
absent | 128 (43.5) | 180 (156.1, 90–200) | 0.105 | 200 (218.8, 200–300) | 0.782 | 90 (110.8, 70–190) | 0.524 | 180 (156.4, 90–200) | 0.69 | |
present | 166 (56.5) | 200 (166.3, 100–200) | 200 (221.8, 200–300) | 90 (105.4, 50–180) | 180 (156.1, 100–200) | |||||
Blood vessel invasion | ||||||||||
absent | 243 (82.7) | 180 (163.4, 100–200) | 0.57 | 200 (220.4, 200–300) | 0.895 | 90 (108.4, 60–180) | 0.836 | 180 (157.5, 90–200) | 0.543 | |
present | 51 (17.3) | 180 (154.3, 90–200) | 200 (220.9, 200–300) | 90 (104.7, 55–145) | 180 (150.0, 100–200) | |||||
ER | ||||||||||
negative | 48 (16.3) | 200 (157.4, 90–200) | 0.97 | 200 (241.7, 200–300) | 0.066 | 95 (121.7, 90–180) | 0.127 | 200 (165.9, 95–200) | 0.226 | |
positive | 246 (83.7) | 180 (162.5, 100–200) | 200 (217.1, 200–300) | 90 (104.9, 60–180) | 180 (154.3, 90–200) | |||||
PgR | ||||||||||
negative | 96 (32.7) | 180 (167.2, 90–200) | 0.605 | 200 (229.5, 200–300) | 0.208 | 90 (110.9, 60–180) | 0.632 | 200 (164.4, 97.5–200) | 0.105 | |
positive | 198 (67.3) | 180 (159.5, 100–200) | 200 (216.7, 200–300) | 90 (106.3, 60–190) | 180 (152.4, 90–200) | |||||
HER2 | ||||||||||
negative | 247 (85.2) | 180 (160.1, 90–200) | 0.161 | 200 (216.8, 200–300) | 0.043* | 90 (108.2, 65–190) | 0.471 | 180 (154.4, 90–200) | 0.207 | |
positive | 43 (14.8) | 200 (176.0, 100–200) | 300 (247.6, 200–300) | 92.5 (108.3, 40–180) | 180 (162.4, 95–200) | |||||
Ki-67 | ||||||||||
< 14 | 68 (23.1) | 160 (136.8, 90–200) | 0.010* | 200 (196.7, 180–250) | 0.011* | 90 (91.7, 55–92.5) | 0.036* | 180 (150.8, 90–200) | 0.603 | |
≥ 14 | 205 (69.7) | 180 (158.9, 95–200) | 200 (225.1, 200–300) | 95 (112.8, 60–190) | 180 (159.5, 90–200) | |||||
Triple negative | ||||||||||
no | 263 (89.5) | 180 (164.4, 100–200) | 0.095 | 200 (219.4, 200–300) | 0.434 | 90 (106.3, 60–180) | 0.106 | 180 (154.9, 90–200) | 0.199 | |
yes | 31 (10.5) | 120 (135.8, 70–200) | 200 (231.2, 200–300) | 97.5 (121.5, 90–190) | 200 (167.8, 90–200) | |||||