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Table 5 Univariate Cox proportional hazards model

From: CD1d- and PJA2-related immune microenvironment differs between invasive breast carcinomas with and without a micropapillary feature

  

Disease free survival

Overall survival

Parameter

Criteria

p

HR (95% CI)

p

HR (95% CI)

Age

< 55 vs. 55 or more

0.556

0.803 (0.386–1.669)

0.322

0.594 (0.212–1.667)

pT

I-II vs. III-IV

0.001*

6.135 (2.123–17.86)

<  0.001*

9.090 (3.247–25.64)

pN

0 vs. 1–3

< 0.001*

4.950 (2.252–10.87)

0.004*

4.150 (1.560–11.11)

pStage

I-II vs. III-IV

0.011*

2.793 (1.267–6.135)

< 0.001*

5.587 (2.212–14.08)

Histological grade

1/2 vs. 3

0.360

1.464 (0.648–3.307)

0.001*

4.782 (1.887–12.12)

ER

Neg. vs. pos.

0.934

0.960 (0.366–2.519)

0.528

0.698 (0.230–2.123)

PgR

Neg. vs. pos.

0.142

0.770 (0.578–1.202)

0.005*

0.246 (0.092–0.656)

Ki-67

< 14% vs. 14% or more

0.237

1.912 (0.653–5.602)

0.310

2.171 (0.486–9.702)

HER2

Neg. vs. pos.

0.600

1.377 (0.416–4.553)

0.779

1.194 (0.335–4.132)

Intrinsic subtype

Triple negative vs. others

0.236

1.792 (0.683–4.695)

0.115

2.445 (0.805–7.463)

IMP

With IMP vs. without IMP

0.064

2.032 (0.958–4.309)

0.308

1.669 (0.624–4.462)

BC-1514 (C15)

< 180 (median) vs. 180 or more

0.476

1.342 (0.597–3.016)

0.304

1.823 (0.580–5.726)

BC-1514 (W12)

< 200 (median) vs. 200 or more

0.613

1.290 (0.480–3.468)

0.365

1.985 (0.451–8.739)

CD1d

< 90 (median) vs. 90 or more

0.674

0.843 (0.381–1.866)

0.391

0.609 (0.196–1.890)

PJA2

< 180 (median) vs. 180 or more

0.454

0.753 (0.357–1.584)

0.742

0.847 (0.315–2.276)

  1. *p < 0.05
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