From: Association of uPA and PAI-1 tumor levels and 4G/5G variants of PAI-1 gene with disease outcome in luminal HER2-negative node-negative breast cancer patients treated with adjuvant endocrine therapy
Biomarker
Relevant event
Yes
No
Wilcoxon rank sum test
uPA values
Mean (SD)
6.5 (4.8)
3.9 (3.5)
p = 0.042
Median (Range)
5.7 (0.5–18.7)
2.7 (0.1–15.5)
PAI-1 values
33.7 (32.7)
18.7 (12.9)
p = 0.037
27.2 (8–140)
15.1 (0–56.8)