From: Statin use and breast cancer survival – a Swedish nationwide study
Breast cancer related death | Overall death | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Pre-diagnostic statin use | Events | Person years | HR | 95% Confidence Intervals | P-value | Events | Person years | HR | 95% Confidence Intervals | P-value |
Statin use rate | ||||||||||
None (n = 15,718) | 1936 | 77,604 | 1.0 | – | – | 3358 | 89,972 | 1.0 | ||
Intermed. (n = 576) | 65 | 2786 | 0.74 | 0.58–0.95 | 0.019 | 297 | 3229 | 0.75 | 0.63–0.89 | 0.001 |
High (n = 1492) | 189 | 7191 | 0.84 | 0.72–0.98 | 0.022 | 216 | 8303 | 0.80 | 0.72–0.89 | < 0.001 |
Regular statin use | ||||||||||
No (n = 7717) | 830 | 33,321 | 1 | – | – | 1467 | 39,566 | 1 | – | – |
Yes (n = 1092) | 111 | 4703 | 0.77 | 0.63–0.95 | 0.014 | 229 | 5566 | 0.76 | 0.66–0.88 | < 0.001 |