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Table 4 The expression of serum exosomal hsa-miR-122-5p in groups based on clinicopathologic factors

From: Identification of non-invasive biomarkers for chronic atrophic gastritis from serum exosomal microRNAs

Variables

 

hsa-miR-122-5p(lg10)

P

Mean ± SD

Age

< 50 (n = 28)

−0.19 ± 0.74

0.09

≥50 (n = 32)

0.16 ± 0.83

 

Gender

Male (n = 26)

−0.007 ± 0.76

1.00

Female (n = 34)

−0.005 ± 0.87

 

Atrophic

Absent (n = 30)

−0.23 ± 0.51

0.01*

Mild (n = 13)

0.22 ± 1.09

 

Moderate (n = 11)

0.55 ± 0.74*a

 

Severe (n = 5)

−0.46 ± 0.93

 

Interestnal metaplasia

Absent (n = 42)

−0.16 ± 0.67*b

< 0.01*

Mild (n = 9)

−0.11 ± 0.77*b

 

Moderate-severe (n = 9)

0.79 ± 0.99

 

Dysplasia

Absent (n = 52)

−0.04 ± 0.83

0.39

Light-median (n = 8)

0.23 ± 0.55

 

Chronic inflammation

Mild (n = 31)

0.06 ± 0.74

0.68

Moderate (n = 24)

−0.02 ± 0.90

 

Severe (n = 5)

−0.24 ± 0.84

 

Active inflammation

No activity (n = 40)

0.01 ± 0.81

0.97

Mild (n = 17)

−0.05 ± 0.83

 

Moderate (n = 3)

−0.02 ± 0.80

 
  1. *aModerate atrophic vs. Absent, P value was 0.036. *bcompare Moderate-severe IM, Absent and Mild IM, P value were 0.001, 0.014, respectively. *P < 0.05