Fig. 2

Methods of analysis used in this study. For each SNP, all four genetic models were considered: additive, dominant, recessive, and co-dominant. However, for some SNPs, the number of patients in a genotype category was zero or very small (<2 patients) when the recessive (for 64,809 SNPs) and co-dominant (for 75,912 SNPs) genetic models were applied. As such, these SNPs were not analyzed under these specific genetic models. HR: hazard ratio; MAF: minor allele frequency; OR: odds ratio; p: metastasis-free survival probability