Fig. 5

Effects of PAHs on HPV-infected cell invasiveness. MCF7, C33A and SiHa cells were exposed to 1 μM of PAHs for three days. Changes of their invasiveness was assessed by the transwell invasion assay and represented by cell invasion index. This index was calculated as the number of invaded cells from experimental groups divided by the control groups in each cell line. #, The invaded cell number of MCF7 was less than 0.01% of initial cell number, and the cell invasion index was set as 1. Data are presented as the mean ± SEM from three independent experiments. Significant level: *p < 0.05, **p < 0.01, ***p < 0.001. BaP, benzo[a]pyrene; DBA, dibenz[a,h]anthracene; IDP, indeno[1,2,3-cd]pyrene; PR, pyrene