Table 2 Treatment, pathological findings, and follow-up of 9 patients with metastatic penile cancer
Author | Time of penile metastasis | Clinical manifestation | Metastatic site | Other metastasis simultaneously | Diagnosis method | Pathology | Treatment of metastasis | Survival time |
|---|---|---|---|---|---|---|---|---|
Gupta NM | 1 week | Painful nodules | Dorsal shaft | Not mentioned | Open biopsy | Squamous cell carcinoma | Polydrug chemotherapy | 6 weeks |
Pai A | 9 months | Painful nodules | Full length | Lymph node in left hilar, subcarinal and left supraclavicular | Fine needle aspiration | Squamous cell carcinoma | Palliative chemotherapy | alive in 6 months |
Zou C | 6 months | Painless mass | Shaft | Right thigh; lymph nodes in left neck | Excisional biopsy | Moderated differentiated squamous cell carcinoma | Resection of penile mass; Palliative external beam radiation | 5 months |
Numakura K | 24+ months | Dysuria, Penile pain Necrosis in glans | Full length | Brain, liver and eyes | Excisional biopsy | Squamous cell carcinoma | Total penectomy, chemotherapy | 3 months |
Kobayashi Y | 2 months | Painless mass | Glans and shaft | Abdominal lymph nodes and spleen | Open biopsy | Squamous cell carcinoma | Chemotherapy | 5 months |
López-Aramburu MA | Simultaneously penile metastasis was the first symptom | Pain, Necrosis in glans | Glans and distal shaft | Right humerus | Excisional biopsy | Squamous cell carcinoma | Partial penectomy | 1 month |
Morán PE | 24+ months | Painless mass, Dysuria | Glans and shaft | Pelvic lymph node | Open biopsy | Squamous cell carcinoma | Chemotherapy plus radiotherapy | Withdrawing, loss to follow up |
Li XM | 9 months | Priapism, Painless nodle, Dysuria | Shaft | Not mentioned | Excisional biopsy | Squamous cell carcinoma | Total penectomy | 10 months |
Tang ZJ | 4 months | Priapism | Shaft | Not mentioned | Excisional biopsy | Moderately differentiated squamous cell carcinoma | Total penectomy | Not mentioned |
Song LM | 12 months | Dysuria Painful nodules | Right shaft | Not detected | Ultrasonic guided biopsy | Moderately differentiated squamous cell carcinoma | Radiotherapy | 4 months |