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Fig. 2 | BMC Cancer

Fig. 2

From: The small molecule Bcl-2/Mcl-1 inhibitor TW-37 shows single-agent cytotoxicity in neuroblastoma cell lines

Fig. 2

a Western Blot of whole cell lysate after transfection with Bcl-2 siRNA and with antibodies against Bcl-2, and the housekeeping protein β-actin. b Apoptosis was measured in Kelly cells after transfection with Bcl-2 siRNA. The enrichment factor was used as a parameter of apoptosis. c Proliferation was measured in Kelly cells after transfection with Bcl-2 siRNA. The proliferation rate is given as a percentage of control. d Western Blot of whole cell lysate after transfection with Mcl-1 siRNA and with antibodies against Mcl-1, and the housekeeping protein β-actin. e Apoptosis was measured in Kelly cells after transfection with Mcl-1 siRNA. The enrichment factor was used as a parameter of apoptosis. f Proliferation was measured in Kelly cells after transfection with Mcl-1 siRNA. The proliferation rate is given as a percentage of control

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