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Table 2 The correlations between the ALI (and its components) and the clinicopathological factors

From: The prognostic significance of the advanced lung cancer inflammation index in patients with unresectable metastatic colorectal cancer: a retrospective study

 

ALI

BMI (kg/m2)

Albumin (g/dl)

NLR

Median (range)

p-value

Median (range)

p-value

Median (range)

p-value

Median (range)

p-value

Age

 < 65

34.17 (4.68–174.81)

 

21.73 (15.48–29.91)

 

4.0 (2.7–4.9)

 

2.66 (0.71–12.57)

 

 ≥ 65

38.52 (4.61–175.07)

0.367

21.50 (15.30–33.76)

0.683

3.8 (2.5–4.8)

0.023

2.18 (0.58–13.56)

0.112

Gender

 Male

38.42 (4.61–174.81)

 

21.80 (15.32–29.91)

 

3.9 (2.5–4.7)

 

2.44 (0.71–13.56)

 

 Female

36.81 (7.41–175.07)

0.341

20.88 (15.30–33.76)

0.246

3.9 (2.9–4.9)

0.714

2.41 (0.58–8.85)

0.459

Location of primary tumor

 Right side

41.44 (4.61–175.07)

 

22.05 (15.32–33.76)

 

3.9 (2.7–4.8)

 

1.95 (0.58–13.56)

 

 Left side

33.70 (7.41–109.73)

0.137

21.39 (15.30–29.91)

0.628

3.95 (2.5–4.9)

0.617

2.53 (0.94–8.85)

0.069

Histological type

 Well, Moderately

36.81 (4.61–175.07)

 

21.50 (15.30–33.76)

 

3.9 (2.5–4.9)

 

2.48 (0.58–13.56)

 

 Poorly, Mucinous

39.39 (12.96–101.80)

0.442

21.79 (16.98–27.34)

0.962

3.9 (3.2–4.6)

0.786

2.03 (1.05–4.95)

0.375

RAS status

 Wild type

40.35 (4.61–109.73)

 

21.20 (15.30–33.76)

 

4.1 (2.5–4.8)

 

2.08 (0.94–13.56)

 

 Mutant type

37.29 (4.68–175.07)

0.203

21.80 (16.00–29.91)

0.652

4.0 (2.7–4.9)

0.829

2.66 (0.58–12.57)

0.075

Detection of unresectable tumor

 Synchronous

28.98 (4.61–175.07)

 

21.49 (16.00–33.76)

 

3.85 (2.5–4.8)

 

2.69 (0.58–13.56)

 

 Metachronous

40.43 (9.31–109.73)

0.016

22.02 (15.30–29.29)

0.680

4.0 (3.1–4.9)

0.020

2.08 (0.97–6.33)

0.028

The number of organs affected by metastasis

 One organ

38.21 (7.41–175.07)

 

21.30 (15.30–29.91)

 

3.9 (2.5–4.9)

 

2.41 (0.58–7.77)

 

 Multiple organs

36.13 (4.61–174.81)

0.968

21.80 (16.89–33.76)

0.535

3.9 (2.7–4.8)

0.718

2.48 (0.71–13.56)

0.930

Peritoneal dissemination

 Negative

35.42 (7.41–175.07)

 

21.60 (15.30–33.76)

 

3.9 (2.5–4.9)

 

2.52 (0.58–8.85)

 

 Positive

39.39 (4.61–98.33)

0.365

21.86 (16.98–25.65)

0.339

4.0 (2.7–4.7)

0.190

2.04 (0.94–13.56)

0.282

Molecular targeted therapy

 Without

35.15 (11.17–174.81)

 

22.44 (16.12–33.76)

 

3.85 (2.5–4.8)

 

2.42 (0.71–6.07)

 

 With

38.42 (4.61–175.07)

0.977

21.00 (15.30–29.91)

0.105

4.0 (2.7–4.9)

0.281

2.41 (0.58–13.56)

0.986

  1. ALI Advanced lung cancer inflammation index, BMI Body mass index, NLR Neutrophil to lymphocyte ratio