Regression of solid breast tumours in mice by Newcastle disease virus is associated with production of apoptosis related-cytokines

Table 3 Activities of ALT, AST and the level of total bilirubin in different groups of mice

Liver Function Tests
Groups	Total Bilirubin [mg/dl]	Aspartate Transaminase (AST) [U/l]	Alanine Transaminase (ALT) [U/l]
NC	3.43 ± 0.40	120.67 ± 1.53	36.00 ± 2.00
CC	2.13 ± 0.95	214.67 ± 1.53 *	53.67 ± 1.53
CT	5.27 ± 0.59	265.00 ± 2.00 *	95.67 ± 1.53 *
NDV8	4.43 ± 0.40	153.33 ± 1.53	38.67 ± 1.53
NDV16	5.75 ± 0.35	125.33 ± 93.82	41.67 ± 1.53
NDV32	4.87 ± 0.35	105.00 ± 1.00	47.00 ± 1.00
NDV64	5.13 ± 0.67	115.00 ± 11.27	52.67 ± 2.51
CNDV8	4.47 ± 0.35	98.67 ± 1.53	26.33 ± 1.15
CNDV16	3.00 ± 0.50	173.33 ± 1.53	57.00 ± 1.00
CNDV32	2.87 ± 0.35	121.00 ± 2.00	49.00 ± 1.00
CNDV64	3.40 ± 0.40	153.67 ± 1.53	49.33 ± 0.58
CNDV8 + T	2.77 ± 0.45	166.67 ± 56.62	103.00 ± 2.00 *
CNDV16 + T	2.43 ± 0.40	108.00 ± 1.00	56.33 ± 1.53
CNDV32 + T	10.67 ± 4.72 *	122.33 ± 2.52	160.33 ± 25.66 *
CNDV64 + T	14.33 ± 4.04 *	170.67 ± 1.53	146.33 ± 32.52 *

NC normal control, CC cancer contro; CT allotransplanted + Tamoxifen, NDV virus alone; CNDV, allotransplanted + virus; CNDV + T, allotransplanted + virus + Tamoxifen; n = 6. Data are shown as mean ± S.D. *p < 0.05 compared with NC

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