Table 1 Detailed Mouse Data from E545K, H1047R or SgPten Combined with c-Met Injected Mice
From: Functional role of SGK3 in PI3K/Pten driven liver tumor development
Injection | Sgk3 genotype | Number | Gender | Weeks post injection | Body weight (g) | Liver weight (g) | Histology |
|---|---|---|---|---|---|---|---|
E545K/c-Met | +/+ | 8 | F | 6.6 | 23.7 | 5.8 | HCC |
F | 8 | 24.2 | 4.7 | HCC | |||
F | 8 | 25.3 | 5.6 | HCC | |||
F | 8.3 | 27.4 | 5.5 | HCC | |||
M | 9 | 32.5 | 7.4 | HCC | |||
F | 9.0 | 26.3 | 5.0 | HCC | |||
M | 10.1 | 31.0 | 7.1 | HCC | |||
M | 11.7 | 31.2 | 6.3 | HCC | |||
−/− | 8 | F | 9.9 | 26.9 | 5.3 | HCC | |
F | 10.0 | 26.5 | 5.2 | HCC | |||
M | 10.1 | 35.4 | 7.4 | HCC | |||
F | 11.7 | 26.4 | 5.4 | HCC | |||
M | 12 | 29.3 | 6.8 | HCC | |||
M | 13.1 | 29.9 | 7.7 | HCC | |||
M | 13.3 | 32.8 | 7.0 | HCC | |||
M | 18.7 | 31.2 | 5.9 | HCC | |||
H1047R/c-Met | +/+ | 5 | F | 5.6 | 26.9 | 5.0 | HCC |
F | 5.9 | 21.3 | 5.9 | HCC | |||
M | 7.1 | 29.3 | 6.4 | HCC | |||
M | 7.6 | 31.3 | 5.9 | HCC | |||
M | 10.6 | 27.8 | 5.0 | HCC | |||
−/− | 5 | F | 5.6 | 28.0 | 6.4 | HCC | |
F | 7.6 | 23.0 | 6.1 | HCC | |||
M | 10.1 | 31.0 | 6.0 | HCC | |||
M | 10.4 | 30.0 | 6.3 | HCC | |||
M | 10.6 | 28.2 | 6.1 | HCC | |||
sgPten/c-Met | +/+ | 6 | F | 8 | 23.1 | 5.3 | HCC |
F | 9.4 | 27.3 | 5.8 | HCC | |||
M | 10.4 | 29.2 | 6.3 | HCC | |||
M | 10.4 | 27.9 | 4.3 | HCC | |||
M | 12.7 | 31.8 | 6.8 | HCC | |||
M | 12.7 | 29.6 | 6.1 | HCC | |||
sgPten/c-Met | −/− | 6 | F | 9.4 | 28.2 | 6.9 | HCC |
M | 9.6 | 27.5 | 7.3 | HCC | |||
F | 10.4 | 27.2 | 7.5 | HCC | |||
F | 12.7 | 26.8 | 5.1 | HCC | |||
F | 15 | 27.8 | 7.0 | HCC | |||
M | 15.6 | 29.2 | 8.1 | HCC |