Overall survival of patients with recurrent pancreatic cancer treated with systemic therapy: a retrospective study

Table 4 Multivariate Cox Regression Model of factors associated with overall survival^a

Factor	Comparison	Hazard Ratio	Lower 95%CL	Upper 95%CL	P-value
Pathologic Stage	IIA vs. I	0.52	0.19	1.40	0.1953
	IIB vs. I	1.70	0.75	3.87	0.2067
	III vs. I	1.19	0.23	6.15	0.8378
Chemotherapy for rPDAC	Yes vs. No	0.14	0.08	0.24	<.0001
Margin negative resection	Yes vs. No	0.57	0.35	0.93	0.0245
Lymphovascular invasion	Yes vs. No	1.15	0.69	1.92	0.5937
Radiotherapy for rPDAC	Yes vs. No	0.28	0.14	0.53	<.0001
Perioperative therapy	Yes vs. No	1.81	1.02	3.22	0.0417
Ca19–9 level at recurrence	Above 1000 U/ml	1.012	1.002	1.023	0.0237
CA19–9 level at diagnosis	Above 1000 U/ml	1.066	1.014	1.122	0.0131

Variables with P value < 0.25 from univariate analysis were included in this model
^aPerioperative therapy: combination of patients who received neoadjuvant or adjuvant therapy

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