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Table 1 Patient characteristics (N = 36)

From: Phase I study of high-dose ascorbic acid with mFOLFOX6 or FOLFIRI in patients with metastatic colorectal cancer or gastric cancer

Characteristics

No. (%)

Age, years

 Median (range)

53 (27–75)

  < 65

28 (77.8)

  ≥ 65

8 (22.2)

Sex

 Male

21 (58.3)

 Female

15 (41.7)

ECOG performance status

 0

2 (5.6)

 1

33 (91.7)

 2

1 (2.8)

Weight, kg, median (range)

57.0 (39.0–77.0)

Cancer type

 Colorectal

30 (83.3)

 Gastric

6 (16.7)

Stage at diagnosis

 Synchronous metastasis

28 (77.8)

 Metachronous metastasis

8 (22.2)

Prior chemotherapy

 Yes

7 (19.4)

 No

29 (80.6)

Previous surgery to the primary site

 Yes

19 (52.8)

 No

17 (47.2)

Add Avastin

 Yes

14 (38.9)

 No

22 (61.1)

RAS and BRAF status

 KRAS mutant

10 (27.8)

 BRAF V600E mutant

2 (5.6)

 RAS and BRAF wild-type

14 (38.9)

 Unknown

10 (27.8)

  1. ECOG Eastern Cooperative Oncology Group