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Table 3 Immunohistochemical ‘intrinsic’ subtypes of groups 1, 2, and 3

From: Array comparative genomic hybridization analysis discloses chromosome copy number alterations as indicators of patient outcome in lymph node-negative breast cancer

Parameter

No. of cases (%)

P

Total

Group 1

Group 2

Group 3

Average age (±SD)

54.5 (±11.3)

51.9 (±6.0)

55.0 (±13.4)

56.1 (±10.9)

 

Stage

 I

9

3 (23)

3 (13)

3 (20)

NS

 II

35

8 (62)

16

(70)

11 (73)

 III

7

2 (15)

4

(17)

1 (7)

Histological type

 Invasive ductal

47

12 (92)

23 (100)

12 (80)

NS

 Invasive lobular3

3

0 (0)

0 (0)

3 (20)

 

 Squamous cell

1

1 (8)

0 (0)

0 (0)

 

Grade

 1 and 2

19

2 (15)

7 (30)

10 (67)

NS

 3

32

11 (85)

16 (70)

5 (33)

 

Immunohistochemical subtype

 Triple negative

11

9 (69)

0 (0)

2 (13)

0.000061

 Luminal A-like

15

2 (15)

4 (17)

9 (60)

 

 Luminal B-like

18

2 (15)

13 (57)

3 (20)

 

 HER2 overexpressing

6

0 (0)

6 (26)

0 (0)

 

 Not identified

1

0 (0)

0 (0)

1 (7)

 

Total

51

13 (100)

23 (100)

15 (100)

 
  1. NS not significant