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Fig. 3 | BMC Cancer

Fig. 3

From: Analysis of hereditary cancer syndromes by using a panel of genes: novel and multiple pathogenic mutations

Fig. 3

mRNA analysis of the c.1166G > T in BMPR1A a. Chromatograms of sequencing analysis of genomic DNA of a patient carrying the c.1166G > T in BMPR1A. b. RT-PCR products on 3% agarose gel. Lane 1: 100 bp DNA Ladder (New England Biolabs), Lanes 2 and 3: the sample of the patient with the variant, Lane 4: normal sample, Lane 5: negative control. c. Chromatograms of sequencing analysis of cDNA A from the same patient. The c.1166 T variant is not present, indicating instability of the aberrantly spliced transcript (top panel: wild type sample, bottom panel: sample of the patient with the variant)

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BMC Cancer

ISSN: 1471-2407

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