Fig. 2From: Comprehensive mutation detection of BRCA1/2 genes reveals large genomic rearrangements contribute to hereditary breast and ovarian cancer in Chinese womenPedigree of families with proband carrying BRCA1 LGRs. a 147th family with proband carrying exon5-7dup. b 10th family with proband carrying exon13-14dup. c 213th family with proband carrying exon13-14dup. d 113th family with proband carrying exon1-22del. e 203th family with proband carrying exon1-22del. (BC, breast cancer; OC, ovarian cancer; Bi-BC, bilateral breast cancer)Back to article page