A clinical model to predict the risk of synchronous bone metastasis in newly diagnosed colorectal cancer: a population-based study

Table 3 Risk factors for bone metastasis of colorectal cancer patients in multivariable logistic regression

Variable	Multivariable analysis
Variable	OR (95% CI)	P Value	Beta cofficients (β)	Scores
Tumor location
Colon	1 [Reference]
Rectum	1.960 (1.412–2.720)	0.000	0.673	2
Grade
Well-Moderate differentiation	1 [Reference]
Poorly-Undifferentiation	1.686 (1.224–2.323)	0.001	0.523	2
Histological type
Adenocarcinoma	1 [Reference]
Signet-ring cell carcinoma	4.904 (2.789–8.623)	0.000	1.590	4
CEA
(−)	1 [Reference]
(+)	2.067 (1.411–3.027)	0.000	0.726	2
N Stage
N0	1 [Reference]
N1/N2	1.471 (1.039–2.082)	0.029	0.386	1
Brain metastasis
No	1 [Reference]
Yes	13.602 (5.774–32.045)	0.000	2.610	6
Liver metastasis
No	1 [Reference]
Yes	8.378 (5.893–11.910)	0.000	2.126	5
Lung metastasis
No	1 [Reference]
Yes	5.563 (4.027–7.684)	0.000	1.716	4

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