| Wine consumption from age 15 years until breast cancer diagnosis, average drinks/week | ||||||
---|---|---|---|---|---|---|---|
Non-drinkers | < 1 | 1–< 3 | ≥3 | P trend | P heterogeneity | ||
Household income, times the federal poverty guideline | |||||||
  < 3 | No. Death | 148 | 67 | 27 | 6 |  |  |
HR (95% CI) | Referent | 0.94 (0.69–1.28) | 0.70 (0.46–1.07) | 0.32 (0.14–0.74) | 0.003 | 0.005 | |
  ≥ 3 | No. Death | 226 | 117 | 50 | 29 |  |  |
HR (95% CI) | Referent | 0.96 (0.74–1.23) | 0.82 (0.59–1.14) | 1.09 (0.72–1.63) | 0.98 |  | |
Race | |||||||
 Black | No. Death | 215 | 75 | 26 | 9 |  |  |
HR (95% CI) | Referent | 1.06 (0.79–1.41) | 0.64 (0.42–0.98) | 0.65 (0.33–1.30) | 0.05 | 0.23 | |
 White | No. Death | 167 | 116 | 54 | 26 |  |  |
HR (95% CI) | Referent | 0.92 (0.71–1.19) | 0.88 (0.64–1.22) | 0.82 (0.53–1.26) | 0.33 |  | |
Education | |||||||
  ≤ High school | No. Death | 185 | 59 | 27 | 13 |  |  |
HR (95% CI) | Referent | 0.82 (0.60–1.12) | 0.88 (0.58–1.35) | 1.09 (0.61–1.96) | 0.93 | 0.11 | |
  > High school | No. Death | 197 | 132 | 53 | 22 |  |  |
HR (95% CI) | Referent | 1.03 (0.80–1.31) | 0.73 (0.52–1.00) | 0.64 (0.40–1.00) | 0.02 |  | |
Menopausal status at diagnosis | |||||||
 Pre-MP | No. Death | 177 | 109 | 49 | 19 |  |  |
HR (95% CI) | Referent | 0.95 (0.73–1.24) | 0.95 (0.68–1.34) | 0.73 (0.44–1.19) | 0.24 | 0.42 | |
 Post-MP | No. Death | 166 | 61 | 21 | 11 |  |  |
HR (95% CI) | Referent | 0.93 (0.68–1.28) | 0.68 (0.43–1.09) | 0.63 (0.34–1.19) | 0.07 |  | |
BMI 5-years before diagnosis (kg/m2) | |||||||
  < 25 | No. Death | 154 | 113 | 53 | 23 |  |  |
HR (95% CI) | Referent | 0.97 (0.75–1.25) | 0.79 (0.57–1.10) | 0.78 (0.49–1.22) | 0.15 | 0.80 | |
  ≥ 25 | No. Death | 228 | 78 | 27 | 12 |  |  |
HR (95% CI) | Referent | 0.96 (0.72–1.27) | 0.75 (0.49–1.14) | 0.73 (0.40–1.33) | 0.17 |  | |
Comorbid conditionb | |||||||
 No | No. Death | 206 | 125 | 53 | 27 |  |  |
HR (95% CI) | Referent | 0.92 (0.72–1.18) | 0.80 (0.58–1.11) | 0.74 (0.48–1.12) | 0.10 | 0.96 | |
 Yes | No. Death | 176 | 66 | 27 | 8 |  |  |
HR (95% CI) | Referent | 1.04 (0.77–1.41) | 0.74 (0.49–1.13) | 0.84 (0.41–1.75) | 0.30 |  | |
Cigarette smoking | |||||||
 Never | No. Death | 227 | 84 | 30 | 10 |  |  |
HR (95% CI) | Referent | 1.06 (0.79–1.41) | 1.00 (0.66–1.51) | 0.69 (0.36–1.33) | 0.34 | 0.77 | |
 Ever | No. Death | 155 | 107 | 50 | 25 |  |  |
HR (95% CI) | Referent | 0.91 (0.70–1.17) | 0.68 (0.49–0.94) | 0.79 (0.51–1.22) | 0.08 |  | |
Stage of breast cancer at diagnosis | |||||||
 Localized | No. Death | 100 | 55 | 27 | 11 |  |  |
HR (95% CI) | Referent | 1.10 (0.78–1.54) | 1.06 (0.69–1.65) | 0.80 (0.42–1.51) | 0.60 | 0.43 | |
 Non-localized | No. Death | 282 | 136 | 53 | 24 |  |  |
HR (95% CI) | Referent | 0.92 (0.73–1.16) | 0.69 (0.50–0.94) | 0.76 (0.49–1.17) | 0.05 |  | |
Estrogen receptor status | |||||||
 Positive | No. Death | 161 | 82 | 40 | 20 |  |  |
HR (95% CI) | Referent | 0.93 (0.70–1.24) | 0.80 (0.55–1.16) | 0.87 (0.53–1.41) | 0.35 | 0.80 | |
 Negative | No. Death | 160 | 93 | 35 | 13 |  |  |
HR (95% CI) | Referent | 1.11 (0.84–1.49) | 0.87 (0.59–1.29) | 0.76 (0.43–1.37) | 0.25 |  | |
Histogologic type | |||||||
 Ductal | No. Death | 286 | 150 | 62 | 24 |  |  |
HR (95% CI) | Referent | 0.97 (0.77–1.22) | 0.74 (0.54–1.00) | 0.66 (0.43–1.03) | 0.02 | 0.33 | |
 Lobular | No. Death | 37 | 25 | 6 | 8 |  |  |
HR (95% CI) | Referent | 1.17 (0.72–1.93) | 0.50 (0.21–1.19) | 1.21 (0.56–2.61) | 0.91 |  |