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Fig. 3 | BMC Cancer

Fig. 3

From: Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

Fig. 3

a Glycolysis, OXPHOS metabolism and ATP production after 0.2 μM MP1 b glycolysis and OXPHOS metabolism and ATP production after 0.50 μM of MP1. Blue line is DMSO control and the red line MP1 treated cells for 18 h, reported as mean ± SD. OXPHOS and glycolysis were measured by oxygen consumption rate (OCR) and extracellular acidification rate (ECAR), respectively. The shape of the OCR and ECAR curves result from the sequential treatment of cells with activators and inhibitors of OXPHOS and glycolysis. Statistical significance defined as p < 0.05

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BMC Cancer

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