Case report of rhabdomyosarcomatous transformation of a primary gastrointestinal stromal tumor (GIST)

BMC Cancer

Table 1 Amino acid changes in Rhabdomyosarcomatous dedifferentiation of GIST as reported in the literature

Morphology^a (dedifferentiated)	Mutation	Amino Acid Change	Reference
Rhabdomyosarcomatous^b	6 nt deletion	KV558–559del and Trp557Phe	our sample
Rhabdomyosarcomatous^b	6 nt deletion	KV558–559	Jiang 2015 [14]
Rhabdomyosarcomatous	Missense	V559D	Zheng 2013 [15]
Rhabdomyosarcomatous	Missense	V559D	Liegl 2009 case 1 [2]
Rhabdomyosarcomatous	18 nt deletion	556–574 del	Liegl 2009 case 2 [2]
Rhabdomyosarcomatous	Missense	V559D	Liegl 2009 case3 [2]
Rhabdomyosarcomatous	54 nt deletion	556–574 del	Liegl 2009 case 4 [2]
Rhabdomyosarcomatous	none	PDGFRA exon 18 del	Liegl 2009 case 5 [2]

^aMorphology: the morphologic findings of dedifferentiated component after TKIs treatment in the metastatic sites and non-metastatic sites including our case^b

ISSN: 1471-2407