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Fig. 6 | BMC Cancer

Fig. 6

From: Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression

Fig. 6

Over-expression of AMOG affects L1 expression and apoptosis-related signaling pathways. Western blot analysis of expression levels of L1 and AMOG (a, e), phosphorylated Akt1 (b, f) and Erk1/2 (c and g), and ratio of Bcl-2/Bax (d, h) in U-87 MG and U251 cells after transfection with an AMOG expression plasmid. Mean values ± SEM are from 3 independent experiments; independent Student’s t-test (*p < 0.05, **p < 0.01, and ***p < 0.001 versus the Control siRNA group)

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