Fig. 7From: Smac mimetics LCL161 and GDC-0152 inhibit osteosarcoma growth and metastasis in miceModel for Smac mimetic anti-osteosarcoma efficacy. Smac mimetic treatment induces osteosarcoma cells to activate TNFR1-mediated cell death pathways in response to TNFα produced by intratumoral immune cellsBack to article page