Skip to main content
Fig. 8 | BMC Cancer

Fig. 8

From: CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts

Fig. 8

A pictorial representation of the interaction between emmprin on tumor cells and CD73 on fibroblasts. Emmprin mainly exists on tumor cells, and CD73 exists both on tumor cells and fibroblasts. Emmprin forms a complex with CD73, and regulates MMP-2 production in co-cultures of tumor cells and fibroblasts. Pro-MMP-2 produced by fibroblasts is probably activated by MT1-MMP expressed on tumor cells

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us