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Table 2 Uni- and multivariable analysis for LNM/LVI of EGC patients in the training set

From: Risk factors of lymph node metastasis or lymphovascular invasion for early gastric cancer: a practical and effective predictive model based on international multicenter data

Parameters

Univariable Analysis

Multivariable Analysis

Odds Ratio (95%CI)

P-value

Odds Ratio (95%CI)

P-value

Age

 ≤ 60

Ref

   

 > 60

0.997 (0.776–1.282)

0.984

  

Sex

 Male

Ref

 

Ref

 

 Female

1.476 (1.135–1.92)

0.004

1.492 (1.134–1.963)

0.004

Tumor location

 

0.714

  

 Upper

Ref

   

 Middle

1.117 (0.765–1.63)

0.568

  

 Lower

1.001 (0.695–1.443)

0.994

  

 Overlapa

1.28 (0.739–2.217)

0.378

  

Tumor size

 ≤ 20 mm

Ref

 

Ref

 

 > 20 mm

1.73 (1.346–2.224)

<  0.001

1.536 (1.184–1.992)

0.001

Depth of invasion

 Mucosa

Ref

 

Ref

 

 Submucosa

2.939 (2.22–3.892)

<  0.001

2.898 (2.177–3.858)

<  0.001

Tumor histological types

 Differentiated

Ref

 

Ref

 

 Undifferentiated

2.03 (1.52–2.71)

<  0.001

1.983 (1.474–2.668)

<  0.001

  1. Abbreviations: Ref reference, CI confidence interval, LVI lymphovascular invasion, EGC early gastric cancer, LNM lymph node metastasis
  2. aOverlap, tumor invaded two or more regions simultaneously
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BMC Cancer

ISSN: 1471-2407

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