DMFS | LRRFS | PFS | OS | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
B | SE | HR(95%CI) | P | B | SE | HR(95%CI) | P | B | SE | HR(95%CI) | P | B | SE | HR(95%CI) | P | |
Gender | ||||||||||||||||
Female | 1 | 1 | 1 | 1 | ||||||||||||
Male | −0.943 | 0.372 | 0.389(0.188–0.808) | 0.011 | 0.189 | 0.280 | 1.208(0.697–2.092) | 0.500 | −0.270 | 0.198 | 0.764(0.518–1.126) | 0.173 | −0.570 | 0.269 | 0.566(0.3340.959) | 0.034 |
Age | ||||||||||||||||
<44 | 1 | 1 | 1 | 1 | ||||||||||||
≥ 44 | −0.106 | 0.223 | 0.900(0.581–1.393) | 0.636 | − 0.380 | 0.248 | 0.684(0.420–1.111) | 0.125 | − 0.242 | 0.152 | 0.785(0.582–1.058) | 0.112 | − 0.288 | 0.187 | 0.750(0.519–1.083) | 0.125 |
Tumor stage | ||||||||||||||||
T1 | 1 | 1 | 1 | 1 | ||||||||||||
T2 | 0.681 | 0.486 | 1.975(0.763–5.116) | 0.161 | −0.145 | 0.736 | 0.865(0.204–3.661) | 0.844 | 0.050 | 0.396 | 1.051(0.484–2.285) | 0.900 | 0.050 | 0.429 | 1.052 (0.454–2.438) | 0.906 |
T3 | −0.213 | 0.450 | 0.808(0.335–1.952) | 0.636 | 0.261 | 0.408 | 1.299(0.583–2.891) | 0.522 | −0.126 | 0.277 | 0.882(0.513–1.517) | 0.650 | −0.584 | 0.358 | 0.557 (0.276–1.125) | 0.103 |
T4 | −0.292 | 0.244 | 0.747(0.463–1.205) | 0.232 | −0.373 | 0.267 | 0.689(0.408–1.162) | 0.162 | −0.577 | 0.162 | 0.562(0.409–0.772) | 0.000 | −1.011 | 0.200 | 0.364 (0.246–0.538) | 0.000 |
Node stage | ||||||||||||||||
N0 | 1 | 1 | 1 | 1 | ||||||||||||
N1 | −1.666 | 0.466 | 0.189(0.076–0.471) | 0.000 | −1.554 | 0.667 | 0.211(0.057–0.782) | 0.020 | −1.443 | 0.342 | 0.236(0.121–0.462) | 0.000 | −1.568 | 0.406 | 0.209(0.094–0.463) | 0.000 |
N2 | −1.960 | 0.325 | 0.141(0.074–0.267) | 0.000 | −0.742 | 0.387 | 0.476(0.223–1.017) | 0.055 | −1.216 | 0.225 | 0.296(0.191–0.460) | 0.000 | −1.392 | 0.258 | 0.249(0.150–0.412) | 0.000 |
N3 | −1.117 | 0.278 | 0.327(0.190–0.564) | 0.000 | −0.472 | 0.380 | 0.624(0.296–1.315) | 0.215 | −0.832 | 0.216 | 0.435(0.285–0.665) | 0.000 | −1.080 | 0.249 | 0.339(0.209–0.553) | 0.000 |
Clinical stage | ||||||||||||||||
III | 1 | 1 | 1 | 1 | ||||||||||||
IV | −0.606 | 0.222 | 0.546(0.353–0.844) | 0.006 | −0.405 | 0.244 | 0.667(0.413–1.076) | 0.097 | −0.674 | 0.151 | 0.510(0.379–0.685) | 0.000 | −1.166 | 0.191 | 0.312(0.214–0.453) | 0.000 |
Target therapy | ||||||||||||||||
Without | 1 | 1 | 1 | 1 | ||||||||||||
With | 0.796 | 0.325 | 2.217(1.174–4.188) | 0.014 | −0.367 | 0.260 | 0.693(0.416–1.154) | 0.158 | 0.292 | 0.187 | 1.340(0.928–1.933) | 0.118 | 0.707 | 0.263 | 2.028(1.213–3.393) | 0.007 |
Induction chemotherapy | ||||||||||||||||
No | 1 | 1 | 1 | 1 | ||||||||||||
Yes | 0.107 | 0.230 | 1.113(0.709–1.747) | 0.642 | −0.354 | 0.270 | 0.702(0.413–1.193) | 0.191 | −0.181 | 0.163 | 0.834(0.607–1.148) | 0.266 | −0.279 | 0.204 | 0.756(0.507–1.128) | 0.170 |