The diversity between curatively resected pancreatic head and body-tail cancers based on the 8th edition of AJCC staging system: a multicenter cohort study

Table 3 Univariate and multivariate analysis for prognostic factors in 351 cases of PC patients with curatively surgical resection

Parameters	median survival (days)	Univariate analysis P (log rank)	Multivariate analysis hazard ratio (95% CI)	P
Age (< 65/ ≥65 years)	432/421	0.127	─
Gender (male/female)	421/472	0.366	─
Tumor location (ph/pbt)	488/340	0.003	1.405(1.082–1.826)	0.011
Tumor size (< 2/ ≥2 cm)	472/421	0.371	─
Tumor size (< 3/ ≥3 cm)	472/418	0.096	─
Well/Moderate/poor Differentiation	452/420/382	0.071	─
T stage (T1 + T2/ T3 + T4)	472/381	0.068	─
Lymph nodes metastasis 8th (N0/N1/N2)	480/330/284	0.001	1.451(1.123–1.874)	0.004
Lymph nodes metastasis 7th (N0/N1 + N2)^a	472/399	0.090	─
8th AJCC stage (I + II /III + VI)	468/284	0.007	1.442(1.085–1.915)	0.012
Perineural invasion (absent/present)	454/400	0.179	─
Vascular permeation (absent/present)	480/330	0.004	1.401(0.905–2.168)	0.131
CA19–9 level (< 37 U/ml/ ≥37 U/ml)	565/395	0.104	─
PLM (absent/present)	499/330	0.000	1.594(1.224–2.076)	0.001
7th AJCC stage	468/172	0.012	Not included

N1 Lymph nodes metastasis 1–3; N2 Lymph nodes metastasis> 3; 7th and 8th AJCC stage 7th and 8th edition of AJCC staging system in PC; Ph Pancreatic head; Pbt Pancreatic body-tail. a In 7th AJCC stage, N1 and N2 combined together

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