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Table 4: Orthotopic injections in NOD/SCID/IL2Rcc-null mice

From: GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma

Cell line

Number of cells engrafted

Treatments

Primary Tumor Volume (mm3)

Metastases

Liver

Lung

SK-N-DZ

1 000 000

Control

3 559

5/5

5/5

GX 15-070

1 630

1/5

5/5

GX 15-070 + HCQa

540

0/5

0/5

  1. aHCQ: Hydroxychloroquine
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BMC Cancer

ISSN: 1471-2407

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