Radiological appearance of hepatocellular carcinoma predicts the response to trans-arterial chemoembolization in patients undergoing liver transplantation

Table 5 Univariate and multivariate analysis of the pre-TACE radiological appearances variables related to near-compete necrosis

Variables	Tumor necrosis < 90%	Tumor necrosis ≥90%	P value
Enhancement pattern in arterial phase
hyperenhancement	19	35	0.002
Hypo/isoenhancement	10	2	0.002
Heterogeneous enhancement
Presence	17	23	0.770
Absence	12	14	0.770
Typical enhancement
Presence	12	27	0.010
Absence	17	10	0.010
Intratumoral necrosis
Presence	2	8	0.190
Absence	27	29	0.190
Attenuation on precontrast phase
Hypoattenuation	5	9	0.485
isoattenuation	24	28	0.485
Tumor margin
Smooth	16	31	0.011
Lobulated/infiltrative	13	6	0.011
Tumor capsular
Presence	9	13	0.726
Absence	20	24	0.726
Radiological classification
Type A	16	35	0.000^a
Type B/Type C	13	2	0.000^a

^aIndependently related to near-complete necrosis on the multivariate analysis (radiological classification RR = 14.2, 95% CI = 2.9–70.6, p = 0.001)

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