Table 4 Characteristics of CK7 and GATA3 double negative Grade 3 breast cancers
Features | CK7−/GATA3- | CK7−/GATA3+ | CK7+/GATA3- | CK7+/GATA3+ | P-value |
|---|---|---|---|---|---|
Counts | 8 (2.4%) | 28 (85.4%) | 51 (15.5%) | 241 (73.5%) | |
Nottingham Grade | <0.0001 | ||||
1 | 0 | 1 (2.3%) | 1 (2.3%) | 41 (95.3%) | |
2 | 1 (1%) | 9 (8.8%) | 5 (5%) | 87 (85.3%) | |
3 | 7 (3.8%) | 18 (9.8%) | 45 (24.5%) | 113 (61.7%) | |
ER (G3 only) | <0.0001 | ||||
Positive | 0 | 14 (17%) | 1 (1%) | 69 (82%) | |
Negative | 7 (7%) | 4 (4%) | 44 (45%) | 43 (43%) | |
PR (HG) | <0.0001 | ||||
Positive | 0 | 15 (21%) | 4 (5%) | 54 (74%) | |
Negative | 7 (6%) | 3 (3%) | 41 (38%) | 58 (53%) | |
Her2 (HG) | 0.4027 | ||||
Positive | 1 (2%) | 5 (12%) | 7 (16%) | 30 (70%) | |
Negative | 6 (4%) | 13 (9%) | 38 (27%) | 92 (59%) |