Table 1 Association analyses of the variants with Esophageal Cancer
From: MassARRAY analysis of twelve cancer related SNPs in esophageal squamous cell carcinoma in J&K, India
S.No | SNP | Gene | p value | OR (95% CI) | HWE | OR (95% CIa) | p valuea |
|---|---|---|---|---|---|---|---|
1 | rs12190287 | TCF21 | 0.008 | 1.4 (1.09–1.8) | 0.126 | 1.3 (1.07–1.8) | 0.002 |
2 | rs10046 | CYP19A1 | 0.0007 | 1.5 (1.21–2.0) | 0.195 | 1.8 (1.1–3.2) | 0.02 |
3 | rs2735940 | TERT | 0.457 | 1.1 (0.84–1.45) | 0.499 | 1.1 (0.4–2.4) | 0.849 |
4 | rs751402 | ERCC5 | 0.597 | 0.9 (0.68–1.24) | 0.847 | 1.2 (0.7–2.0) | 0.535 |
5 | rs2699887 | PIK3CA | 0.063 | 0.7 (0.49–1.02) | 0.117 | 1.8 (1.0–3.2) | 0.03 |
6 | rs3792152 | REV1 | 0.094 | 1.2 (0.96–1.60) | 0.412 | 1.5 (0.8–2.8) | 0.170 |
7 | rs10069690 | TERT | 0.994 | 0.9 (0.72–1.3) | 0.709 | 1.0 (0.5–1.7) | 0.952 |
8 | rs2981582 | FGFR2 | 0.594 | 1.1 (0.82–1.39) | 0.067 | 1.3 (0.7–2.1) | 0.314 |
9 | rs1695 | GSTP1 | 0.723 | 1.1 (0.77–1.43) | 0.908 | 1.3 (0.7–2.3) | 0.269 |
10 | rs251796 | TERF2 | 0.299 | 0.8 (0.65–1.13) | 0.864 | 0.7 (0.4–1.2) | 0.270 |
11 | rs2229080 | DCC | 0.199 | 1.1 (0.91–1.54) | 0.113 | 0.6 (0.2–1.2) | 0.173 |
12 | rs1801018 | BCL2 | 0.999 | 1.0 (0.77–1.29) | 0.125 | 0.9 (0.5–1.6) | 0.773 |