Table 4 Fusion genes with possible functional change (Fusion between gene 1 and gene 2 were observed)
Case | Mean distance | Gene 1 | Gene 2 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
Gene | Cytoband | Breakpoint | Transcript | Gene | Cytoband | Breakpoint | Transcript | |||
1 | 230,509 | ROS1 | 6q21-q22 | Chr6: 117639431 | NM_002944 | GOPC | 6q21 | Chr6: 117913860 | NM_020399 | Glioblastoma, Cholangiocarcinoma, ovarian cancer, NSCLC [14] |
2 | 68,411 | TACC3 | 4p16.3 | Chr4: 1736923 | NM_006342 | FGFR3 | 4p16.3 | Chr4: 1806178 | NM_000142 | Glioblastoma, bladder urothelial tumors, nasopharyngeal carcinoma, head and neck cancer, cervical cancer [15] |