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Table 1 Correlation of the clinical characteristics with mutation status in Breast cancer cases

From: Screening of BRCA1/2 genes mutations and copy number variations in patients with high risk for hereditary breast and ovarian cancer syndrome (HBOC)

clinical characteristics

Total

BRCA1/2 Carriers

non Carriers

P-value

Histological type

0.8

 ductal carcinoma

45 (91.8%)

12 (92.3)

33(91.6)

 lobular carcinoma

3 (6.1%)

1(7.6)

2(5.5)

 Others

1 (2.04%)

0

1(2.7)

Tumor size

0.7

 T1

14(28.5%)

3(23.0%)

11(30.5%)

 T2

22(44.8%)

5(38.4%)

17(47.2%)

 T3

11(22.4%)

4(30.7%)

7(19.4%)

 T4

2(4.08%)

1(7.6%)

1(2.7%)

SBR grade

0.9

 I

6(12.2%)

2(15.3%)

4(11.1%)

 II

23(46.9%)

6(46.1%)

17(47.2%)

 III

20(40.8%)

5(38.4%)

15(41.6%)

Molecular type

0.03

 triple negative

17 (34.6%)

8 (61.5%)

9 (25.0)

 luminal

29 (59%)

5 (38.4%)

24(66.6)

 HER2+

3 (6.1%)

0(0%)

3(8.3)