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Table 1 The comparison of clinical and genetic features between LINC00649-high and LINC00649-low groups. A total of 145 patients from TCGA and 451 patients form BeatAML database were included. The molecular and cytogenetic risk of LINC00649-low group is more adverse than that of LINC00649-high group (p < 0.001)

From: LINC00649 underexpression is an adverse prognostic marker in acute myeloid leukemia

 

TCGA

beatAML

LINC00649-low group (n = 72)

LINC00649-high group (n = 73)

p value

LINC00649-low group (n = 225)

LINC00649-high group (n = 226)

p value

Age (year)

55.21 ± 2.011

54.47 ± 2.137

0.81

59.81 ± 1.055

53.62 ± 1.356

0.049

Gender

  

0.589

  

0.775

 Female

27

31

 

95

98

 

 Male

35

31

 

130

127

 

Race

  

0.838

  

0.801

 White

47

45

 

39

37

 

 Other races

15

17

 

186

188

 

Mutation count

9.82 ± 0.624

9.77 ± 0.803

0.962

NA

NA

 

Risk stratification of cytogenetics

 

0.001

  

NA

 Good

0

15

 

NA

NA

 

 Intermediate

48

28

 

NA

NA

 

 Poor

14

19

 

NA

NA

 

Risk stratification of molecular mutation

 

0.001

  

0.002

 Good

0

15

 

99

70

 

 Intermediate

45

28

 

44

73

 

 Poor

17

19

 

82

82

 

WBC

47.498 ± 5.091

22.705 ± 5.040

0.001

34.807 ± 2.979

27.615 ± 3.465

0.112