Fig. 8From: microRNA-451a promoter methylation regulated by DNMT3B expedites bladder cancer development via the EPHA2/PI3K/AKT axisSchematic diagram. DNMT3B inhibits miR-451a transcription by methylation modification of the miR-451a promoter, thus activating EPHA2 and the following PI3K/AKT signaling, leading to BCa progressionBack to article page