Group | pCR | Covariate | P value | |||
---|---|---|---|---|---|---|
Molecular subtypes | ||||||
HR+/HER2- | HR+/HER2+ | HR-/HER2+ | TNBC | |||
Intervention | n = 9 | n = 12 | n = 2 | n = 2 | ||
+ | 0 | 7 (58.3) | 0 | 1 (50.0) | 0.014 | |
- | 9 (100.0) | 5 (41.7) | 2 (100.0) | 1 (50.0) | ||
Control | n = 12 | n = 11 | n = 2 | n = 2 | ||
+ | 1 (8.3) | 5 (45.5) | 1 (50.0) | 1 (50.0) | 0.125 | |
- | 11 (91.7) | 6 (54.5) | 1 (50.0) | 1 (50.0) | ||
Total | n = 21 | n = 23 | n = 4 | n = 4 | ||
+ | 1 (4.8) | 12 (52.2) | 1 (25.0) | 2 (50.0) | 0.002 | |
- | 20 (95.2) | 11 (47.8) | 3 (75.0) | 2 (50.0) | ||
ER Status | ||||||
positive | negative | |||||
Intervention | n = 21 | n = 4 | ||||
+ | 7 (33.3) | 1 (25.0) | 1.00 | |||
- | 14 (66.7) | 3 (75.0) | ||||
Control | n = 23 | n = 4 | ||||
+ | 6 (26.1) | 2 (50.0) | 0.558 | |||
- | 17 (73.9) | 2 (50.0) | ||||
Total | n = 44 | n = 8 | ||||
+ | 13 (29.5) | 3 (37.5) | 0.689 | |||
- | 31 (70.5) | 5 (62.5) | ||||
PR Status | ||||||
positive | negative | |||||
Intervention | n = 14 | n = 11 | ||||
+ | 4 (28.6) | 4 (36.3) | 1.00 | |||
- | 10 (71.4) | 7 (63.6) | ||||
Control | n = 19 | n = 8 | ||||
+ | 5 (26.3) | 3 (37.5) | 0.658 | |||
- | 14 (73.7) | 5 (62.5) | ||||
Total | n = 33 | n = 19 | ||||
+ | 9 (27.3) | 7 (36.8) | 0.472 | |||
- | 24 (72.7) | 12 (63.1) | ||||
HER2 Status | ||||||
positive | negative | |||||
Intervention | n = 10 | n = 15 | ||||
+ | 5 (50.0) | 3 (20.0) | 0.194 | |||
- | 5 (50.0) | 12 (80.0) | ||||
Control | n = 8 | n = 19 | ||||
+ | 5 (62.5) | 3 (15.8) | 0.027 | |||
- | 3 (37.5) | 16 (84.2) | ||||
Total | n = 18 | n = 34 | ||||
+ | 10 (55.5) | 6 (17.6) | 0.005 | |||
- | 8 (44.4) | 28 (82.3) | ||||
ki67 status | ||||||
positive | negative | |||||
Intervention | n = 19 | n = 6 | ||||
+ | 8 (42.1) | 0 (0) | 0.129 | |||
- | 11 (57.9) | 6 (100.0) | ||||
Control | n = 15 | n = 12 | ||||
+ | 6 (40.0) | 2 (16.7) | 0.236 | |||
- | 9 (60.0) | 10 (83.3) | ||||
Total | n = 34 | n = 18 | ||||
+ | 14 (41.2) | 2 (11.1) | 0.025 | |||
- | 20 (58.8) | 16 (88.9) | ||||
TILS | ||||||
positive | negative | |||||
Intervention | n = 10 | n = 15 | ||||
+ | 6 (60.0) | 2 (13.3) | 0.028 | |||
- | 4 (40.0) | 13 (86.7) | ||||
Control | n = 13 | n = 14 | ||||
+ | 5 (38.5) | 3 (21.4) | 0.420 | |||
- | 8 (61.5) | 11 (78.6) | ||||
Total | n = 23 | n = 29 | ||||
+ | 11 (47.8) | 5 (17.2) | 0.018 | |||
- | 12 (52.2) | 24 (82.7) |