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Table 1 Patient characteristics

From: Randomized phase II study comparing the efficacy and safety of SOX versus mFOLFOX6 as neoadjuvant chemotherapy without radiotherapy for locally advanced rectal cancer (KSCC1301)

Characteristics

SOX arm

n=53 (%)

mFOLFOX6 arm

n=50 (%)

p-value

Age (years)

 Median (range)

63 (37–79)

64 (36–79)

0.3440

Sex

 Male

44 (83.0)

40 (80.0)

0.6930

 Female

9 (17.0)

10 (20.0)

 

Performance status (ECOG)

 0

53 (100.0)

48 (96.0)

0.2332

 1

0 (0.0)

2 (4.0)

 

Depth of wall invasion

 T3

39 (73.6)

37 (74.0)

0.9618

 T4

14 (26.4)

13 (26.0)

 

Lymph node metastasis

 N0

20 (37.7)

16 (32.0)

0.6317

 N1

20 (37.7)

20 (40.0)

 

 N2

13 (24.5)

12 (24.0)

 

 N3a

0 (0.0)

2 (4.0)

 

RAS status

 Unexamined

37 (70.0)

36 (72.0)

0.5945

 Wild

8 (15.1)

11 (22.0)

 

 Mutant

8 (15.1)

3 (6.0)

 

Past illness/comorbidity

 Yes

23 (43.4)

23 (46.0)

1.0000

 Cerebral infarction

2 (3.8)

3 (6.0)

 

 Myocardial infarction

1 (1.9)

0 (0.0)

 

 Hypertension

15 (28.3)

14 (28.0)

 

 Diabetes

8 (15.1)

8 (16.0)

 

 Others

11 (20.8)

11 (22.0)

 
  1. aLymph node in the inferior mesenteric artery region,
  2. ECOG: Eastern Cooperative Oncology Group, SOX: S-1 and oxaliplatin, mFOLFOX6: folinic acid, 5-FU, and oxaliplatin