Fig. 1

Copy number alterations (CNAs) in small intestinal neuroendocrine tumors (SINETs). a CGH analysis of 131 SINETs revealed that the most frequent chromosomal rearrangement is hemizygous loss of chromosomes 9, 13, 18 and 22 and gain of 4, 5, 7, 14 and 20. b and c. Gain of chromosomes 4, 5, 7, 10, 14 and 20 was more frequent in tumors without hemizygous loss of chromosome 18 (n = 38) compared to SINETs with hemizygous loss of chromosome 18 (n = 93). (d) The average number of CNAs including all fragments larger than 500 kb was similar in tumors with (15.2 ± 1.3) or without loss of chromosome 18 (14.7 ± 2.2)