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Fig. 1 | BMC Cancer

Fig. 1

From: Diverse mechanisms activate the PI 3-kinase/mTOR pathway in melanomas: implications for the use of PI 3-kinase inhibitors to overcome resistance to inhibitors of BRAF and MEK

Fig. 1

Genetic variants of the PI3K pathway genes. DNA extracted from NZM cell lines was subjected to whole-exome sequencing. The top row indicates the number of variants per cell line for the genes included. Middle rows indicate colour-coded individual variants found in 52 NZM cell lines. Side panels indicate the percentage of cell lines with mutations per gene. The bottom row indicates cell line names

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