Risk factors for pegylated liposomal doxorubicin-induced moderate to severe hand-foot syndrome in breast cancer patients: assessment of baseline clinical parameters

Table 4 Logistic multivariate regression analysis results

Influencing factors	B	OR	95%CI	P
BMI	0.110	1.116	1.043–1.194	0.002**
Dose intensity	0.234	1.264	1.190–1.343	<0.001**
Baseline ALT	0.018	1.018	0.992–1.045	0.169
Baseline AST	-0.025	0.975	0.931–1.022	0.290
History of gallstones	1.225	3.403	1.123–10.316	0.030*
Peripheral blood circulation	0.681	1.975	1.169–3.338	0.011*
Sweat excretion	1.073	2.925	1.652–5.178	<0.001**
With or without tumour?	0.364	1.440	0.901–2.299	0.127
HER2	0.680	1.973	1.201–3.242	0.007**
Constant	−11.138	<0.001		<0.001

* p < 0.05 ** p < 0.01
Enter quantitative data directly, and the classification data is based on the negative group
Abbreviations: ALT alanine aminotransferase, AST aspartate aminotransferase, HER2 human epidermalgrowth factor receptor-2

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