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Table 4 Overall survival analysis in advanced-stage patients who received or did not receive angiogenesis inhibitors

From: Assessing tumor angiogenesis using dynamic contrast-enhanced integrated magnetic resonance-positron emission tomography in patients with non-small-cell lung cancer

 

2-year overall survival (%)

p-value*

Angiogenesis inhibitors received

(n = 11)

Angiogenesis inhibitors not received

(n = 47)

MTV (cm3)

  ≥ 30

100.0

48.1

0.046‡

  < 30

71.4

71.4

0.334

Ktrans (10−3 min−1)

  ≥ 200

85.7

60.3

0.069

  < 200

66.7

57.8

0.436

kep (10−3 min−1)

  ≥ 900

85.7

59.3

0.048‡

  < 900

66.7

57.8

0.488

  1. Abbreviations: MR-PET = magnetic resonance positron emission tomography; MTV = metabolic tumor volume; Ktrans = volume transfer constant; kep = reverse reflux rate constant
  2. * Significance was tested using Kaplan–Meier analysis and log-rank tests
  3. ‡ p-values < 0.05 were considered statistically significant