Table 2 Sample descriptive statisticsa
Outcome measures | Available case sample by variable | Complete case sample 1951 | Imputation sample 6351 |
|---|---|---|---|
n (%) | % (SE for the percentage) | ||
Harmful alcohol (Yes) | 3167 | 273 (18.9%) | 16% (0.6) |
No | Â | 1169 (81.1%) | 84% (0.6) |
Daily smoking (Yes) | 3195 | 121 (8.3%) | 14% (0.6) |
No | Â | 1330 (91.7%) | 86% (0.6) |
Nicotine dependence (Yes) | 3193 | 50 (3.5%) | 6% (0.4) |
No | Â | 1400 (96.6%) | 94% (0.4) |
Obesity (Yes) | 3202 | 183 (12.6%) | 11% (0.5) |
No | Â | 1270 (88%) | 89% (0.5) |
High waist circumference (Yes) | 3194 | 411 (28.3%) | 29% (0.7) |
No | Â | 1042 (71.7%) | 71% (0.7) |
High waist-hip ratio (Yes) | 3194 | 114 (7.9%) | 10% (0.4) |
No | Â | 1339 (92.2%) | 90% (0.4) |
Exposure measure | |||
 Cancer Risk Exposure AUC (0–21) | 1951 |  |  |
 Mean (SD) |  | 9.57 (4.21) | 9.72 (3.98) |
 Median (IQR) |  | 8.75 (6.5–12) | 9.63 (6.6–12.1) |
Confounder measures | |||
 Sex | 6351 |  |  |
  Female |  | 1171 (60%) | 52% (0.6) |
  Male |  | 780 (40%) | 48% (0.6) |
 Maternal education | 5540 |  |  |
  Degree |  | 458 (24%) | 17% (0.5) |
  A level |  | 562 (29%) | 28% (0.6 |
  O level |  | 632 (33%) | 35% (0.6) |
   < O level |  | 271 (14%) | 20% (0.5) |
 Parental socioeconomic position | 5319 |  |  |
  Professional |  | 401 (21%) | 17% (0.5) |
  Managerial and technical |  | 886 (47%) | 45% (0.7) |
  Skilled non-man |  | 417 (22%) | 24% (0.6) |
  Skilled man, part or unskilled |  | 169 (9%) | 14% (0.5) |
 Housing tenure | 6169 |  |  |
  Mortgage/owned |  | 1704 (89%) | 84% (0.5) |
  Private rent |  | 91 (5%) | 8% (0.4) |
  Subsidised rent |  | 127 (7%) | 8% (0.3) |
 Income | 5105 |  |  |
  High |  | 490 (27%) | 24% (0.6) |
  Mid-high |  | 454 (25%) | 22% (0.6) |
  Middle |  | 394 (22%) | 21% (0.6) |
  Mid-low |  | 305 (17%) | 19% (0.6) |
  Low |  | 183 (10%) | 15% (0.5) |
 IQ: mean (SD) | 5433 | 109.8 (16.18) | 105.4 (17.53) |
Maternal smoking | 5342 | 218 (12%) | 18% (0.5) |
 No |  | 1632 (88%) | 82% (0.5) |
Harmful maternal alcohol consumption | 5170 | 481 (27%) | 25% (0.6) |
No | Â | 1321 (73%) | 75% (0.6) |
Maternal cannabis use | 5377 | 58 (3%) | 4% (0.3) |
 No |  | 1798 (97%) | 96% (0.3) |
Maternal physical activity (hrs per week): mean (SD) | 5604 | 3.35 (5.38) | Mean = 3.96 (6.38) |
Birthweight: mean (SD) | 5347 | 3437.5 (507.6) | Mean = 3440 (559.45) |
Gestational age: mean (SD) | 5347 | 276.8 (11.9) | Mean = 276.2 (13.55) |
Maternal unhealthy diet: mean (SD) | 5201 | 0.03 (0.79) | Mean = 0.08 (0.80) |
Child depressive symptoms short moods and feelings questionnaire (SMFQ): mean (SD) | 5347 | 2.27 (2.93) | Mean = 2.47 (3.19) |
Child antisocial behaviour: mean (SD) | 5276 | 0.26 (0.68) | Mean = 0.34 (0.80) |
Child total difficulties score strengths and difficulties questionnaire (SDQ): mean (SD) | 5459 | 6.00 (4.42) | Mean = 6.58 (4.78) |
Adverse childhood experiences (ACEs): mean (SD) | 3396 | 1.03 (1.21) | Mean = 1.31 (1.59) |
Maternal Body mass index (BMI): mean (SD) | 5749 | 22.59 (3.52) | Mean = 22.88 (3.98) |