Table 3 Comparison of characteristics, efficacy and safety in patients undergoing ultrasound-guided lung biopsy between 16-gauge and 18-gauge core biopsy needle when number of pleural surface crossed was 2
Variable | Overall cohort | Propensity-score matched cohort | ||||
|---|---|---|---|---|---|---|
16-gauge (n = 147) | 18-gauge (n = 647) | P value | 16-gauge (n = 145) | 18-gauge (n = 145) | P value | |
Age (years) | 57.8 ± 14.2 | 60.6 ± 12.4 | 0.016 | 58.3 ± 13.6 | 58.1 ± 13.3 | 0.889 |
Gender | ||||||
Male/female | 94/53 | 436/211 | 0.424 | 94/51 | 96/49 | 0.805 |
Patient position | ||||||
Supine/prone/lateral | 52/69/26 | 232/313/102 | 0.846 | 51/69/25 | 48/74/23 | 0.840 |
Emphysema on CT | 16 (10.9%) | 91 (14.1%) | 0.308 | 16 (11.0%) | 18 (12.4%) | 0.715 |
Location of pulmonary lesion (%) | ||||||
Left upper lobe | 27 (18.4%) | 128 (19.8%) | 0.831 | 27 (18.7%) | 31 (21.4%) | 0.465 |
Left lower lobe | 35 (23.8%) | 144 (22.2%) | 34 (23.4%) | 42 (29.0%) | ||
Right upper lobe | 34 (23.1%) | 174 (26.9%) | 34 (23.4%) | 32 (22.0%) | ||
Right middle lobe | 12 (8.2%) | 51 (7.9%) | 12 (8.3%) | 14 (9.7%) | ||
Right lower lobe | 39 (26.5%) | 150 (23.2%) | 38 (26.2%) | 26 (17.9%) | ||
Diameter of lesion (cm) | 4.8 ± 2.6 | 5.3 ± 2.6 | 0.025 | 4.8 ± 2.6 | 5.0 ± 2.4 | 0.582 |
< 5/≥5 | 70/77 | 313/334 | 0.868 | 68/77 | 69/76 | 0.906 |
Proportion of necrosis in the lesion | ||||||
< 50%/≥50% | 123/24 | 523/124 | 0.425 | 121/24 | 113/32 | 0.234 |
Success rate (%) | 141 (95.9%) | 580 (89.6%) | 0.017 | 139 (95.9%) | 128 (88.3%) | 0.017 |
Malignant | 76 (51.7%) | 393 (60.7%) | < 0.001 | 76 (52.4%) | 89 (61.4%) | 0.003 |
Benign | 65 (44.2%) | 187 (28.9%) | 63 (43.5%) | 39 (26.9%) | ||
Non-diagnostic | 6 (4.1%) | 67 (10.4%) | 6 (4.1%) | 17 (9.7%) | ||
Complication rate (%) | 12 (8.2%) | 56 (8.7%) | 0.847 | 11 (7.6%) | 10 (6.9%) | 0.821 |
Pneumothorax | 3 (2.0%) | 14 (2.2%) | 1.000 | 3 (2.1%) | 4 (2.8%) | 1.000 |
Major | 2 (1.4%) | 2 (0.3%) | 0.158 | 2 (1.4%) | 1 (0.7%) | 1.000 |
Minor | 1 (0.7%) | 12 (1.9%) | 0.514 | 1 (0.7%) | 3 (2.1%) | 0.615 |
Hemorrhage | 8 (5.5%) | 44 (6.8%) | 0.209 | 7 (4.8%) | 6 (4.1%) | 0.777 |
Major | 0 (0%) | 0 (0%) | – | 0 (0%) | 0 (0%) | – |
Minor | 8 (5.5%) | 44 (6.8%) | 0.548 | 7 (4.8%) | 6 (4.1%) | 0.777 |
Vasovagal reaction | 1 (0.7%) | 0 (0%) | 0.185 | 1 (0.7%) | 0 (0%) | 1.000 |