Table 4 Toxicities of induction chemotherapy with TPF in patients treated for locally advanced head and neck cancer. Toxicity was assessed according to CTCAE classification V4.0
Grade ≥ 3 | Grade 4 | Grade 5 | |
|---|---|---|---|
Anemia | 16 (14%) | 0 (0%) | 0 (0%) |
Neutropenia | 39 (35%) | 32 (34%) | 2 (2%) |
Febrile neutropenia | 30 (27%) | 1 (1%) | 5 (6%) |
Thrombocytopenia | 7 (6%) | 1 (1%) | 1 (1%) |
Nausea/Vomiting | 24 (22%) | 2 (3%) | 0 (0%) |
Mucositis | 20 (18%) | 1 (2%) | 0 (0%) |
Diarrhea | 19 (17%) | 0 (0%) | 0 (0%) |
Nephrotoxicity | 0 (0%) | 0 (0%) | 0 (0%) |
Digestive hemorrhage | 6 (5%) | 1 (1%) | 1 (1%) |