Fig. 2

Result of Neoadjuvant Chemotherapy and Immediate Breast Reconstruction following with PMRT in Advanced Breast Cancer. a This is a case of left invasive ductal carcinoma with lymph node involvement. The clinical stage was T3N1M0. She received neoadjuvant chemotherapy with 4 cycles of Taxotere and epirubicin. b, c, d The patient initially underwent left nipple-sparing mastectomy. However, nipple core frozen section revealed cancer involvement, and the mastectomy had to be converted to skin-sparing mastectomy. As a result, a larger skin paddle was required from the DIEP flap to compensate for the mastectomy skin defect. The reconstruction was finished with a free DIEP flap immediately after mastectomy. After surgery, the patient received adjuvant chemotherapy with 3 cycles of CEF and 3 cycles of Taxotere, adjuvant radiotherapy and hormone therapy with tamoxifen. At the 39-month follow-up, an acceptable reconstructive outcome with minimal contracture and skin reactions was achieved after radiotherapy