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Table 3 Reconstructive complication analysis among patients with and without NACT

From: Reconstructive outcome analysis of the impact of neoadjuvant chemotherapy on immediate breast reconstruction: a retrospective cross-sectional study

Short-term complication (<  30 days)

All

NACT

Non-NACT

OR (95% CI) of NACT

p value

 Any complication

50 (19.2)

10 (21.7)

40 (18.7)

1.56 (0.63–3.86)

0.334

 Re-exploration

3 (1.2)

1 (2.2)

2 (0.9)

0.79 (0.00–145.23)

0.930

 Infection

2 (0.8)

0 (0.0)

2 (0.9)

N/A

N/A

 Mastectomy skin flap necrosis

15 (5.8)

3 (6.5)

12 (5.6)

1.28 (0.29–5.60)

0.743

 Nipple necrosis

6 (2.3)

2 (4.3)

4 (1.9)

1.57 (0.19–13.09)

0.675

 Seroma

7 (2.7)

1 (2.2)

6 (2.8)

1.58 (0.15–16.81)

0.707

 Hematoma

4 (1.5)

2 (4.3)

2 (0.9)

N/A

N/A

 Expander/Implant exposure

1 (0.4)

0 (0.0)

1 (0.5)

N/A

N/A

 Poor wound healing

33 (12.7)

5 (10.9)

28 (13.1)

1.00 (0.32–3.10)

0.996

 Implant failure

1 (0.4)

0 (0.0)

1 (0.5)

N/A

N/A

Long-term complication (>  30 days)

 Any complication

45 (17.3)

8 (17.4)

37 (17.3)

0.71 (0.25–1.96)

0.502

 Infection

11 (4.2)

4 (8.7)

7 (3.3)

3.26 (0.69–15.26)

0.134

 Expander/Implant exposure

4 (1.5)

0 (0.0)

4 (1.9)

N/A

N/A

 Implant rupture

9 (3.5)

0 (0.0)

9 (4.2)

N/A

N/A

 Capsular contracture

24 (9.2)

3 (6.5)

21 (9.8)

0.37 (0.08–1.67)

0.195

 Contracture release

13 (5.0)

1 (2.2)

12 (5.6)

0.15 (0.01–1.93)

0.144

 Implant failure

15 (5.8)

0 (0.0)

15 (7.0)

N/A

N/A

  1. NACT neoadjuvant chemotherapy, N/A not applicable