Fig. 1From: ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genesCholesterol biosynthesis genes are induced by A1542 in leukemic cells. a Diagram of cholesterol biosynthesis pathway. b RNAseq data for cholesterol biosynthesis genes after treatment of HEL for 24 h with A1542. c Level of total cholesterol in HEL cells treated with A1542 (2uM) and DMSO for 24 h. d-e Q-RT-PCR analysis of indicated genes after A1542 treatment of HEL cells for 24 h versus vehicle (DMSO)Back to article page