Table 2 Operating characteristics for the platform design with primary endpoint of disease control rate (DCR)
Control Arm | n = 30 for experimental arms | ||||
|---|---|---|---|---|---|
Experiment Arm 1 | Experiment Arm 2 | Experiment Arm 3 | Experiment Arm 4 | ||
True DCR | 0.70 | 0.70 | 0.80 | 0.90 | 0.95 |
Number of patients | 42.6 | 30.0 | 30.0 | 30.0 | 30.0 |
Start Time (months) | 0 | 0 | 6 | 12 | 18 |
Probability of claiming success | – | 0.148 | 0.441 | 0.833 | 0.964 |