Table 3 Screening for anti-LUAD/COVID-19 drugs based on cMap
Rank | cMap name | Mean | Number | Enrichment | P-value |
|---|---|---|---|---|---|
1 | Puromycin | − 0.729 | 4 | − 0.959 | 0 |
2 | Emetine | − 0.522 | 4 | − 0.83 | 0.00151 |
3 | Glycocholic acid | − 0.506 | 4 | − 0.815 | 0.00211 |
4 | Chicago Sky Blue 6B | − 0.337 | 4 | − 0.797 | 0.00336 |
5 | Nitrofural | − 0.297 | 4 | − 0.781 | 0.00462 |
6 | Cephaeline | − 0.36 | 5 | − 0.758 | 0.00154 |
7 | Pepstatin | − 0.326 | 4 | − 0.711 | 0.0141 |
8 | Cinoxacin | − 0.569 | 4 | − 0.711 | 0.01414 |
9 | 4-Hydroxyphenazone | − 0.356 | 5 | − 0.702 | 0.00511 |
10 | Oxymetazoline | − 0.502 | 4 | − 0.702 | 0.01647 |
11 | Primidone | − 0.347 | 4 | − 0.671 | 0.02626 |
12 | Lycorine | − 0.34 | 5 | − 0.669 | 0.00917 |
13 | Parthenolide | − 0.548 | 4 | − 0.661 | 0.02998 |
14 | Sulindac | − 0.437 | 7 | − 0.654 | 0.00178 |
15 | Citalopram | − 0.318 | 4 | − 0.642 | 0.03929 |
16 | N-acetylmuramic acid | − 0.322 | 4 | − 0.64 | 0.03995 |
17 | Tropine | − 0.357 | 4 | − 0.639 | 0.04084 |
18 | Ciclosporin | − 0.29 | 6 | − 0.594 | 0.01577 |
19 | Benzamil | − 0.302 | 6 | − 0.542 | 0.03665 |